GHK was originally isolated from human plasma in 1973 and its wound repair properties were observed in 1985. In 1999, researchers concluded that GHK or its Cu complex functioned as an activator of tissue remodeling. It is also a signal peptide that promotes extra large collagen aggregates degradation in scars, regular collagen synthesis in normal skin,elastin,proteoglycans and glycosaminoglycans production,growth rate and migration of different cell types and anti-inflammatory and anti-oxidatant response.
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